Why agitate platelets

We accept that at the point where platelets are issued to hospitals, there will have been no more than 16 hours of periods of interruptions of non-agitation in most instances it will be far less than 16 hours.

Hospitals, therefore, have a maximum of 8 hours of non-agitation which needs to include the time taken for the delivery. If you have periods of interruptions which exceed 8 hours you should contact Hospital Services and request the audit trail for individual units.

NHSBT uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve our services, any data collected is anonymised. Abstracts Home. Abstracts Archive. Search Abstracts. Ichikawa: None. Kouta: None. Komori: None. Introduction Acute normovolemic hemodilution ANH is the removal of whole blood WB shortly after the induction of anesthesia and reinfusion of the stored blood at the end of the surgical procedure. ANH can reduce the need for allogeneic blood transfusion.

Furthermore, cold-stored platelets reduce the risk of bacterial contamination and may preserve hemostatic function better compared with platelets at room temperaurtre. Study design and methods: PCs were prepared by the platelet-rich plasma method and stored for 5 days at 20 to 24 degrees C; agitation was interrupted for 1 to 3 days either by simply stopping the agitator or by placing the PCs in a stationary shipping container. Measurements of platelet metabolism and quality were made during storage and on Day 5.

Results: With interruption on the agitator, the production of lactic acid was increased during the interruption in proportion to the number of platelets in the PC and the duration of the interruption.

The pO 2 was increased during agitation interruption, which suggested a decline in oxygen utilization. With the use of the hypotonic shock response and the extent of shape change as reflections of platelet quality, there was no evidence of platelet damage unless the pH fell to or below 6.